Optimizing mesenchymal stem cell therapy: from isolation to GMP-compliant expansion for clinical application

Optimizing mesenchymal stem cell therapy: from isolation to GMP-compliant expansion for clinical application

Abstract Background Mesenchymal stem cells (MSCs) are promising for cell-based therapies targeting a wide range of diseases. However, challenges in translating MSC-based therapies to clinical applications necessitate standardized protocols following Good Manufacturing Practices (GMP) guidelines. Thi...

Full description

Saved in:
Bibliographic Details
Main Authors: Michael E. Williams, Federica Banche Niclot, Sara Rota, Jaesang Lim, Janaina Machado, Ricardo de Azevedo, Katia Castillo, Samuel Adebiyi, Ranga Sreenivasan, Daniel Kota, Patrick C. Mcculloch, Francesca Taraballi
Format: Article
Language:English
Published: BMC 2025-05-01
Series:BMC Molecular and Cell Biology
Subjects:
Mesenchymal stem cells
Infrapatellar fat pad-derived MSCs
Stem cell therapy
Good manufacturing practices
Translational research
Online Access:https://doi.org/10.1186/s12860-025-00539-7
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://doi.org/10.1186/s12860-025-00539-7

Similar Items