Region-specific neuroprotective effects of meldonium pretreatment in two models of sepsis-associated encephalopathy
Sepsis-associated encephalopathy (SAE) is a common yet poorly understood complication of sepsis, which poses a burden in clinical settings, as its management relies on supportive care without targeted pharmacological interventions. Meldonium is a drug approved for ischemic heart disease but has also...
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| Main Authors: | Aleksandra Ružičić, Tijana Srdić, Katarina Bobić, Dunja Drakulić, Filip Veljković, Ana Todorović, Siniša Đurašević, Iva Lakić |
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| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2025-04-01
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| Series: | Frontiers in Pharmacology |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fphar.2025.1588831/full |
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