Region-specific neuroprotective effects of meldonium pretreatment in two models of sepsis-associated encephalopathy

Sepsis-associated encephalopathy (SAE) is a common yet poorly understood complication of sepsis, which poses a burden in clinical settings, as its management relies on supportive care without targeted pharmacological interventions. Meldonium is a drug approved for ischemic heart disease but has also...

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Bibliographic Details
Main Authors: Aleksandra Ružičić, Tijana Srdić, Katarina Bobić, Dunja Drakulić, Filip Veljković, Ana Todorović, Siniša Đurašević, Iva Lakić
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-04-01
Series:Frontiers in Pharmacology
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Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2025.1588831/full
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