Cancer‐Associated Fibroblasts: Heterogeneity, Cancer Pathogenesis, and Therapeutic Targets

Cancer‐Associated Fibroblasts: Heterogeneity, Cancer Pathogenesis, and Therapeutic Targets

ABSTRACT Cancer‐associated fibroblasts (CAFs) are functionally diverse stromal regulators that orchestrate tumor progression, metastasis, and therapy resistance through dynamic crosstalk within the tumor microenvironment (TME). Recent advances in single‐cell multiomics and spatial transcriptomics ha...

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Bibliographic Details
Main Authors: Yutao Li, Qingyun Liu, Xilin Jing, Yuqi Wang, Xiaohua Jia, Xing Yang, Kezhong Chen
Format: Article
Language:English
Published: Wiley 2025-07-01
Series:MedComm
Subjects:
cancer‐associated fibroblasts
heterogeneity
pathogenesis
theranostic
tumor microenvironment
Online Access:https://doi.org/10.1002/mco2.70292
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https://doi.org/10.1002/mco2.70292

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