Phenotypic Shifts in Macrophages Within Advanced Atherosclerotic Plaques in Humans

Phenotypic Shifts in Macrophages Within Advanced Atherosclerotic Plaques in Humans

ABSTRACT The importance of macrophage polarization through atherogenesis is established. However, most studies rely on immunohistological approaches, which have several limitations, such as precluding comprehensive phenotypic analysis. The aim of this study was to perform an alternative analysis of...

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Main Authors: Barbora Muffova, Sona Kauerova, Hana Bartuskova, Karel Paukner, Libor Janousek, Helena Cermakova, Jiri Fronek, Marek Kollar, Marek Petras, Jan Pitha, Rudolf Poledne, Ivana Kralova Lesna
Format: Article
Language:English
Published: Wiley 2025-06-01
Series:FASEB BioAdvances
Subjects:
atherosclerotic plaques
comparison
flow cytometry
macrophage polarization
macrophages (subsets)
non‐atherosclerotic vessels
Online Access:https://doi.org/10.1096/fba.2025-00037
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https://doi.org/10.1096/fba.2025-00037

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