D2 receptor antagonist raclopride regulates glutamatergic neuronal activity in the pedunculopontine nucleus in a rat model of Parkinson's disease

Parkinson disease (PD) is defined by the loss of dopamine (DA). Changes in the pedunculopontine nucleus (PPN), particularly in local field potential (LFP), can be attributed to deficits in DA and DA receptor expression levels. PPN is a heterogeneous nucleus consisting of cholinergic, γ-aminobutyric...

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Bibliographic Details
Main Authors: Hongli Chang, Bo Liu, Hongguang Chang, Na Li, Min Xu, Guilai Zuo, Wubing He, Xuenan Wang
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2024-12-01
Series:Biomedical Technology
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Online Access:http://www.sciencedirect.com/science/article/pii/S2949723X24000321
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