Effects of missed anti-tuberculosis therapy doses on treatment outcome: a multi-center cohort studyResearch in context

Effects of missed anti-tuberculosis therapy doses on treatment outcome: a multi-center cohort studyResearch in context

Summary: Background: Tuberculosis (TB) remains a leading cause of infectious disease mortality globally. Although directly observed therapy (DOT) has been widely implemented to improve adherence, nonadherence continues to compromise treatment success rates, especially in real-world settings. Theref...

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Main Authors: Isabella B.B. Ferreira, Rodrigo C. Menezes, Mariana Araújo-Pereira, Valeria C. Rolla, Afrânio L. Kritski, Marcelo Cordeiro-Santos, Timothy R. Sterling, Cody Staats, Gustavo Amorim, Anete Trajman, Bruno B. Andrade, A. Benjamin, Q. Medeiros, F. Ridolfi, A. Gomes-Silva, J. Oliveira, J. Marine, B. Durovni, S. Cavalcante, A. Rezende, A. Bezerra, A. Carvalho, A. Brito, A. Costa, R. Spener-Gomes, M. Rocha, V. Nascimento, B. Nogueira, A. Andrade, E. Silva
Format: Article
Language:English
Published: Elsevier 2025-08-01
Series:The Lancet Regional Health. Americas
Subjects:
Tuberculosis
Adherence
Treatment
Compliance
Unfavorable treatment outcome
Online Access:http://www.sciencedirect.com/science/article/pii/S2667193X25001723
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