Efficient construction of rAAV-based gene targeting vectors by Golden Gate cloning

The recombinant adeno-associated virus (rAAV) has proven to be an efficient and attractive tool for targeted genome engineering. Here we present a novel method employing the Golden Gate cloning strategy for fast and efficient construction of rAAV-based gene knockout or single-nucleotide knockin vect...

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Bibliographic Details
Main Authors: Yonglun Luo, Lin Lin, Lars Bolund, Charlotte Brandt Sørensen
Format: Article
Language:English
Published: Taylor & Francis Group 2014-05-01
Series:BioTechniques
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Online Access:https://www.future-science.com/doi/10.2144/000114169
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