Increased apoptosis of peripheral blood mononuclear cells in patients with perennial allergic asthma/rhinitis: relation to serum markers of apoptosis
Background: The goal of our study was to examine spontaneous and stimulated apoptosis of peripheral blood MNC from allergic patients, sensitized to Der p I antigen as compared to cells from non-atopic subjects. Furthermore we aimed to investigate which populations of mononuclear cells (lymphocytes,...
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| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2002-01-01
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| Series: | Mediators of Inflammation |
| Online Access: | http://dx.doi.org/10.1080/09629350290000087 |
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| _version_ | 1832549262116782080 |
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| author | Janina Grzegorczyk Marek L. Kowalski Anna Pilat Jolanta Iwaszkiewicz |
| author_facet | Janina Grzegorczyk Marek L. Kowalski Anna Pilat Jolanta Iwaszkiewicz |
| author_sort | Janina Grzegorczyk |
| collection | DOAJ |
| description | Background: The goal of our study was to examine spontaneous and stimulated apoptosis of peripheral blood MNC from allergic patients, sensitized to Der p I antigen as compared to cells from non-atopic subjects. Furthermore we aimed to investigate which populations of mononuclear cells (lymphocytes, monocytes) undergo the apoptosis and to determine relations between apoptosis and serum levels of sFas/APO-1, ICE/caspase-1 or TNF-α. |
| format | Article |
| id | doaj-art-c4905045843447ec996cf0094c2df858 |
| institution | Kabale University |
| issn | 0962-9351 1466-1861 |
| language | English |
| publishDate | 2002-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Mediators of Inflammation |
| spelling | doaj-art-c4905045843447ec996cf0094c2df8582025-02-03T06:11:42ZengWileyMediators of Inflammation0962-93511466-18612002-01-0111422523310.1080/09629350290000087Increased apoptosis of peripheral blood mononuclear cells in patients with perennial allergic asthma/rhinitis: relation to serum markers of apoptosisJanina Grzegorczyk0Marek L. Kowalski1Anna Pilat2Jolanta Iwaszkiewicz3Department of Clinical Immunology and Allergy, Faculty of Medicine, Medical University of Lodz, 251 Pomorska St., Lodz 92-213, PolandDepartment of Clinical Immunology and Allergy, Medical University of Lodz, Lodz, PolandDepartment of Clinical Immunology and Allergy, Medical University of Lodz, Lodz, PolandDepartment of Clinical Immunology and Allergy, Medical University of Lodz, Lodz, PolandBackground: The goal of our study was to examine spontaneous and stimulated apoptosis of peripheral blood MNC from allergic patients, sensitized to Der p I antigen as compared to cells from non-atopic subjects. Furthermore we aimed to investigate which populations of mononuclear cells (lymphocytes, monocytes) undergo the apoptosis and to determine relations between apoptosis and serum levels of sFas/APO-1, ICE/caspase-1 or TNF-α.http://dx.doi.org/10.1080/09629350290000087 |
| spellingShingle | Janina Grzegorczyk Marek L. Kowalski Anna Pilat Jolanta Iwaszkiewicz Increased apoptosis of peripheral blood mononuclear cells in patients with perennial allergic asthma/rhinitis: relation to serum markers of apoptosis Mediators of Inflammation |
| title | Increased apoptosis of peripheral blood mononuclear cells in patients
with perennial allergic asthma/rhinitis: relation to serum markers of apoptosis |
| title_full | Increased apoptosis of peripheral blood mononuclear cells in patients
with perennial allergic asthma/rhinitis: relation to serum markers of apoptosis |
| title_fullStr | Increased apoptosis of peripheral blood mononuclear cells in patients
with perennial allergic asthma/rhinitis: relation to serum markers of apoptosis |
| title_full_unstemmed | Increased apoptosis of peripheral blood mononuclear cells in patients
with perennial allergic asthma/rhinitis: relation to serum markers of apoptosis |
| title_short | Increased apoptosis of peripheral blood mononuclear cells in patients
with perennial allergic asthma/rhinitis: relation to serum markers of apoptosis |
| title_sort | increased apoptosis of peripheral blood mononuclear cells in patients with perennial allergic asthma rhinitis relation to serum markers of apoptosis |
| url | http://dx.doi.org/10.1080/09629350290000087 |
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