Synthesis and in vitro/in silico evaluation of the antimalarial activity of potential amino-quinoline derivatives

In this study, a series of N-arylamino-7-chloroquinolines were synthesized via an alkylation reaction involving aniline derivatives (2) and 4,7-dichloroquinoline (1). Additionally, the synthesis of a library of N-aryl-N-benzylamino-7-chloroquinoline analogues, modified on the aniline nitrogen, has a...

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Bibliographic Details
Main Authors: Moussa Touré, Abdoulaye Gassama, Oumar Sambou, Christian Cavé, Sandrine Cojean
Format: Article
Language:English
Published: Elsevier 2025-04-01
Series:European Journal of Medicinal Chemistry Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2772417424001134
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