SENP2 regulates UCP1-dependent thermogenesis in brown adipocytes via deSUMOylation of ERRα

SENP2 regulates UCP1-dependent thermogenesis in brown adipocytes via deSUMOylation of ERRα

Abstract Brown adipose tissue (BAT) is responsible for energy homeostasis and adaptive thermogenesis. SUMO-specific protease 2 (SENP2) plays an essential role in adipogenesis; however, the role of SENP2 in BAT metabolism has not been explored. Here we investigated the role of SENP2 in mature brown a...

Full description

Saved in:
Bibliographic Details
Main Authors: Hun Jee Choe, Ji Seon Lee, Jong Yoen Park, Seung-Ah Lee, Young Joo Park, Sung Soo Chung, Kyong Soo Park
Format: Article
Language:English
Published: Nature Publishing Group 2025-06-01
Series:Experimental and Molecular Medicine
Online Access:https://doi.org/10.1038/s12276-025-01458-5
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://doi.org/10.1038/s12276-025-01458-5

Similar Items