HIV-1 subtype C-infected individuals maintaining high viral load as potential targets for the "test-and-treat" approach to reduce HIV transmission.

HIV-1 subtype C-infected individuals maintaining high viral load as potential targets for the "test-and-treat" approach to reduce HIV transmission.

The first aim of the study is to assess the distribution of HIV-1 RNA levels in subtype C infection. Among 4,348 drug-naïve HIV-positive individuals participating in clinical studies in Botswana, the median baseline plasma HIV-1 RNA levels differed between the general population cohorts (4.1-4.2 log...

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Main Authors: Vladimir Novitsky, Rui Wang, Hermann Bussmann, Shahin Lockman, Marianna Baum, Roger Shapiro, Ibou Thior, Carolyn Wester, C William Wester, Anthony Ogwu, Aida Asmelash, Rosemary Musonda, Adriana Campa, Sikhulile Moyo, Erik van Widenfelt, Madisa Mine, Claire Moffat, Mompati Mmalane, Joseph Makhema, Richard Marlink, Peter Gilbert, George R Seage, Victor DeGruttola, M Essex
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-04-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0010148&type=printable
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https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0010148&type=printable

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