Induction of an anti-tumor immune response by sonodynamic therapy, combining 5-aminolevulinic acid and high-intensity focused ultrasound using the trigger pulse sonication

Induction of an anti-tumor immune response by sonodynamic therapy, combining 5-aminolevulinic acid and high-intensity focused ultrasound using the trigger pulse sonication

Ultrasound-based cancer therapies offer non-invasive treatment options for deep-seated tumors, yet their clinical application is often limited by safety concerns. High-intensity focused ultrasound (HIFU) has demonstrated therapeutic potential, but its high-power requirements can damage surrounding h...

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Bibliographic Details
Main Authors: Tohru Satoh, Rui Tada, Taiki Yamaguchi, Yoko Endo-Takahashi, Takashi Kanno, Mai Hayakawa, Yoshiyuki Adachi, Yoichi Negishi, Jun Okamoto, Shin Yoshizawa, Ken Masamune
Format: Article
Language:English
Published: Elsevier 2025-12-01
Series:WFUMB Ultrasound Open
Subjects:
high-intensity focused ultrasound
sonodynamic therapy
5-Aminolevulinic acid
protoporphyrin IX
reactive oxygen species
tumor immunity
Online Access:http://www.sciencedirect.com/science/article/pii/S2949668325000102
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