DSS1 is required for proper Integrator–PP2A function

DSS1 is required for proper Integrator–PP2A function

Abstract Integrator–PP2A (INTAC) is a highly modular complex orchestrating the transition of paused RNA polymerase II into productive elongation or promoter-proximal premature termination, with its loss resulting in transcription dysregulation and genome instability. Here, we identify human DSS1—a f...

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Main Authors: Congling Xu, Qian-Xing Zhou, Hai Zheng, Aixia Song, Wen-Ying Zhao, Ting-Ting Xu, Yan Xiong, Yi-Jie Zhang, Zixuan Huang, Yanhui Xu, Jingdong Cheng, Fei Xavier Chen
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-61257-4
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https://doi.org/10.1038/s41467-025-61257-4

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