Omission of axillary lymph node dissection in patients with breast cancer with axillary pathological complete response confirmed by stained region lymph node biopsy after neoadjuvant systemic therapy (SrLNB study): study protocol for a single-arm, single-centre, phase-II trial

Omission of axillary lymph node dissection in patients with breast cancer with axillary pathological complete response confirmed by stained region lymph node biopsy after neoadjuvant systemic therapy (SrLNB study): study protocol for a single-arm, single-centre, phase-II trial

Introduction Given that axillary lymph node dissection (ALND) may not contribute to local control or survival and could lead to increased arm morbidity, axillary de-escalation procedures have replaced ALND in patients achieving axillary pathologic complete response (apCR) after neoadjuvant systemic...

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Main Authors: Yuanyuan Wang, Rui Chen, Xuan Li, Jue Wang, Jingjing Ding, Lexin Wang, Lingjun Ma, Ran Zheng, Yichun Gong, Hao Yao, Xiaoming Zha, Mingyu Wang, Xingye Sheng
Format: Article
Language:English
Published: BMJ Publishing Group 2025-03-01
Series:BMJ Open
Online Access:https://bmjopen.bmj.com/content/15/3/e092563.full
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https://bmjopen.bmj.com/content/15/3/e092563.full

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