The role of METTL14 in the progression of chronic myeloid leukemia

The role of METTL14 in the progression of chronic myeloid leukemia

Objectives Chronic myeloid leukemia (CML), a clonal malignant disease arising from the BCR-ABL fusion gene, presents significant therapeutic challenges, particularly in chemotherapy resistance. The role of METTL14, a key m6A methyltransferase, is implicated in cancer biology, but its role in CML rem...

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Main Authors: Jing Zhang, Zhi-Hua Liao, Yan-Mei Xu, Shu-Qi Li, Fang-Min Zhong, Ling Zhang, Fang-Yi Yao, Qin Bai, Li-Hua Yao, Bo Huang, Jing Liu, Xiao-Zhong Wang
Format: Article
Language:English
Published: Taylor & Francis Group 2025-12-01
Series:Hematology
Subjects:
CML
METTL14
N6-methyladenine
Bcl-x
Alternative splicing
resistance
Online Access:https://www.tandfonline.com/doi/10.1080/16078454.2025.2535819
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https://www.tandfonline.com/doi/10.1080/16078454.2025.2535819

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