Methodology and Application of Adaptive and Sequential Approaches in Contemporary Clinical Trials
The clinical trial, a prospective study to evaluate the effect of interventions in humans under prespecified conditions, is a standard and integral part of modern medicine. Many adaptive and sequential approaches have been proposed for use in clinical trials to allow adaptations or modifications to...
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| Main Authors: | Zhengjia Chen, Yichuan Zhao, Ye Cui, Jeanne Kowalski |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2012-01-01
|
| Series: | Journal of Probability and Statistics |
| Online Access: | http://dx.doi.org/10.1155/2012/527351 |
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