Methodology and Application of Adaptive and Sequential Approaches in Contemporary Clinical Trials

The clinical trial, a prospective study to evaluate the effect of interventions in humans under prespecified conditions, is a standard and integral part of modern medicine. Many adaptive and sequential approaches have been proposed for use in clinical trials to allow adaptations or modifications to...

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Bibliographic Details
Main Authors: Zhengjia Chen, Yichuan Zhao, Ye Cui, Jeanne Kowalski
Format: Article
Language:English
Published: Wiley 2012-01-01
Series:Journal of Probability and Statistics
Online Access:http://dx.doi.org/10.1155/2012/527351
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