Comparative clinical outcomes of acenocoumarol versus direct oral anticoagulants (DOACs) and warfarin in patients with atrial fibrillation: real-world-evidence (SIESTA-A study)

Comparative clinical outcomes of acenocoumarol versus direct oral anticoagulants (DOACs) and warfarin in patients with atrial fibrillation: real-world-evidence (SIESTA-A study)

ObjectiveThe aim of this study was to evaluate the effectiveness and safety of direct oral anticoagulants (DOACs: dabigatran, rivaroxaban, apixaban and edoxaban) and warfarin versus acenocoumarol in patients with atrial fibrillation under real-world clinical practice conditions.MethodsThis was a ret...

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Main Authors: Ma Carmen Montero-Balosa, Juan A. Limón-Mora, Ana Leal-Atienza, Beatriz García-Robredo, Pablo Sánchez-Villegas, Rebeca Isabel-Gómez, Ma José Aguado-Romeo, Luis Gabriel Luque Romero, Ma Teresa Molina-López
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-08-01
Series:Frontiers in Pharmacology
Subjects:
oral anticoagulant agents
oral direct anticoagulants
safety
health outcomes
effectiveness
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2025.1548298/full
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https://www.frontiersin.org/articles/10.3389/fphar.2025.1548298/full

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