Leucine rich repeat containing 15 promotes triple-negative breast cancer proliferation and invasion via the ITGB1/FAK/PI3K signalling pathway

Leucine rich repeat containing 15 promotes triple-negative breast cancer proliferation and invasion via the ITGB1/FAK/PI3K signalling pathway

Abstract Leucine rich repeat containing 15 (LRRC15) is recognized for its intimate association with the extracellular matrix, where it modulates fibroblast function and shapes the immune landscape within the tumour microenvironment. The specific expression patterns and molecular contributions of LRR...

Full description

Saved in:
Bibliographic Details
Main Authors: Xiao Wu, Yameng Liu, Yinxi Hu, Fang Su, Zishu Wang, Yongxia Chen, Zhixiang Zhuang
Format: Article
Language:English
Published: Nature Portfolio 2025-04-01
Series:Scientific Reports
Subjects:
LRRC15
TNBC
ITGB1/FAK/PI3K signalling pathway
Proliferation
Invasion
Online Access:https://doi.org/10.1038/s41598-025-98661-1
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://doi.org/10.1038/s41598-025-98661-1

Similar Items