Genkwanin glycosides are major active compounds in Phaleria nisidai extract mediating improved glucose homeostasis by stimulating glucose uptake into adipose tissues

Genkwanin glycosides are major active compounds in Phaleria nisidai extract mediating improved glucose homeostasis by stimulating glucose uptake into adipose tissues

Abstract Natural remedies are used as standalone treatments or complementary to modern medicine to control type 2 diabetes. In Palau, the traditional leaf decoction of Phaleria nisidai (PNe) is selected to treat hyperglycemia and its efficacy has been supported by a small clinical trial. As part of...

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Main Authors: Carla Horvath, Joëlle Houriet, Alexandra Kellenberger, Caroline Moser, Lucia Balazova, Miroslav Balaz, Hua Dong, Aron Horvath, Isabel Reinisch, Vissarion Efthymiou, Adriano Rutz, Laurence Marcourt, Christopher Kitalong, Bertrand Graz, Victor Yano, Emerson Ferreira Queiroz, Jean-Luc Wolfender, Christian Wolfrum
Format: Article
Language:English
Published: Nature Portfolio 2025-08-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-62689-8
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https://doi.org/10.1038/s41467-025-62689-8

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