Clozapine prevented social interaction deficits and reduced c-Fos immunoreactivity expression in several brain areas of rats exposed to acute restraint stress.

Clozapine prevented social interaction deficits and reduced c-Fos immunoreactivity expression in several brain areas of rats exposed to acute restraint stress.

In the present study, we evaluate the effect of acute restraint stress (15 min) of male Wistar rats on social interaction measurements and c-Fos immunoreactivity (c-Fos-ir) expression, a marker of neuronal activity, in areas involved with the modulation of acute physical restraint in rats, i.e., the...

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Main Authors: Rodolpho Pereira de Oliveira, José Simões de Andrade, Marianna Spina, João Vítor Chamon, Paulo Henrique Dias Silva, Ana Keyla Werder, Daniela Ortolani, Lucas de Santana Cardoso Thomaz, Simone Romariz, Daniel Araki Ribeiro, Beatriz Monteiro Longo, Regina Célia Spadari, Milena de Barros Viana, Liana Melo-Thomas, Isabel Cristina Céspedes, Regina Cláudia Barbosa da Silva
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0262728&type=printable
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https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0262728&type=printable

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