A self-directed Trojanbot-enzymatic nanobot in neutrobot for active target therapy of glioblastoma

Abstract Chemotherapy is an important treatment for glioblastoma (GBM) and a key component of comprehensive GBM therapy. However, the blood-brain barrier (BBB) and complex tumor microenvironment (TME) restrict the diffusion of drugs, which greatly reduces the chemotherapeutic effect on GBM. Single s...

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Bibliographic Details
Main Authors: Yuanyuan Gao, Meng Mao, Yue Li, Mingjun Xuan, Yingjie Wu, Qiang He
Format: Article
Language:English
Published: Nature Portfolio 2025-06-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-60422-z
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