The impact of imputation on meta-analysis of genome-wide association studies.

Genotype imputation is often used in the meta-analysis of genome-wide association studies (GWAS), for combining data from different studies and/or genotyping platforms, in order to improve the ability for detecting disease variants with small to moderate effects. However, how genotype imputation aff...

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Bibliographic Details
Main Authors: Jian Li, Yan-fang Guo, Yufang Pei, Hong-Wen Deng
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0034486&type=printable
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