Linear dicentric chromosomes in bacterial natural isolates reveal common constraints for replicon fusion

Linear dicentric chromosomes in bacterial natural isolates reveal common constraints for replicon fusion

ABSTRACT Multipartite bacterial genome organization can confer advantages, including coordinated gene regulation and faster genome replication, but is challenging to maintain. Agrobacterium tumefaciens lineages often contain a circular chromosome (Ch1), a linear chromosome (Ch2), and multiple plasmi...

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Bibliographic Details
Main Authors: Ram Sanath-Kumar, Arafat Rahman, Zhongqing Ren, Ian P. Reynolds, Lauren Augusta, Clay Fuqua, Alexandra J. Weisberg, Xindan Wang
Format: Article
Language:English
Published: American Society for Microbiology 2025-06-01
Series:mBio
Subjects:
Agrobacterium tumefaciens
chromosome fusion
multipartite genome
Hi-C
natural isolates
Online Access:https://journals.asm.org/doi/10.1128/mbio.01046-25
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https://journals.asm.org/doi/10.1128/mbio.01046-25

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