TRPC6-targeted dexamethasone nanobubbles with ultrasound-guided theranostics for adriamycin-induced nephropathy

Abstract Background Glucocorticoid (GC) intolerance and systemic toxicity pose significant challenges in the treatment of primary nephrotic syndrome (PNS), underscoring the urgent need for targeted therapies that maximize efficacy while minimizing adverse effects. To address these challenges, we dev...

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Bibliographic Details
Main Authors: Lin Wu, Yang Liu, Ziqi Fu, Honglei Guo, Kang Liu, Jiafa Ren, Zhimin Huang, Fang Yang, Huijuan Mao
Format: Article
Language:English
Published: BMC 2025-05-01
Series:Journal of Nanobiotechnology
Online Access:https://doi.org/10.1186/s12951-025-03487-8
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