Target liquid biopsy using “enriched” polymerase chain reaction and DNA melting analysis

Target liquid biopsy using “enriched” polymerase chain reaction and DNA melting analysis

Objective: to evaluate the possibility of using a highly sensitive method of “enriched” polymerase chain reaction followed by DNA melting analysis (PCR-DMA) for target liquid biopsy of cancer patients.Materials and methods. The “enriched” PCR-DMA was used for mutation scanning of KRAS (codons 12 and...

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Main Authors: I. V. Botezatu, I. O. Panchuk, A. A. Kolomeytseva, A. A. Fedenko, N. N. Mazurenko, I. V. Tsyganova, O. Yu. Susova, V. N. Kondratova, V. P. Shelepov, A. V. Lichtenstein
Format: Article
Language:Russian
Published: ABV-press 2018-05-01
Series:Успехи молекулярной онкологии
Subjects:
liquid biopsy
mutation scanning
dna melting analysis
kras
Online Access:https://umo.abvpress.ru/jour/article/view/134
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