Incidence of upper respiratory tract infections with biological therapies in moderate to severe atopic dermatitis: a systematic review and meta-analysis

Incidence of upper respiratory tract infections with biological therapies in moderate to severe atopic dermatitis: a systematic review and meta-analysis

IntroductionAtopic dermatitis (AD) is a chronic inflammatory skin condition affecting 5%−20% of children and 2%−10% of adults worldwide. Treatment for moderate-to-severe AD includes biologics like dupilumab, tralokinumab, lebrikizumab, and JAK inhibitors (abrocitinib, upadacitinib). However, upper r...

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Main Authors: Rose Alraddadi, Mulham Kalantan, Yara Aljefri, Hadeel Maaddawi, Abdulrahman Alsamadani, Athoub Kadasa, Abdulrahman Softah, Baraa Tabbakh, Rahaf Alturkistani, Abdulhadi Jfri
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-04-01
Series:Frontiers in Medicine
Subjects:
atopic dermatitis
biologics
dupilumab
IL4/13 inhibitor
tralokinumab
lebrikizumab
Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2025.1550640/full
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https://www.frontiersin.org/articles/10.3389/fmed.2025.1550640/full

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