Caspase-3 is transiently activated without cell death during early antigen driven expansion of CD8(+) T cells in vivo.
<h4>Background</h4>CD8(+) T cell responses develop rapidly during infection and are swiftly reduced during contraction, wherein >90% of primed CD8(+) T cells are eliminated. The role of apoptotic mechanisms in controlling this rapid proliferation and contraction of CD8(+) T cells rema...
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| Main Authors: | Scott McComb, Rebecca Mulligan, Subash Sad |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2010-12-01
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| Series: | PLoS ONE |
| Online Access: | https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0015328&type=printable |
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