Caspase-3 is transiently activated without cell death during early antigen driven expansion of CD8(+) T cells in vivo.

<h4>Background</h4>CD8(+) T cell responses develop rapidly during infection and are swiftly reduced during contraction, wherein >90% of primed CD8(+) T cells are eliminated. The role of apoptotic mechanisms in controlling this rapid proliferation and contraction of CD8(+) T cells rema...

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Bibliographic Details
Main Authors: Scott McComb, Rebecca Mulligan, Subash Sad
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-12-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0015328&type=printable
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