A Survival Case in a Severe Amlodipine Intoxication
Calcium channel blockers (CCBs) are prescribed in a wide variety of cardiovascular conditions. Nevertheless, they remain a major cause of cardiovascular drug overdose that often leads to a lethal outcome. We report the case of an intoxication with amlodipine, which caused severe hypotension, in a yo...
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| Format: | Article |
| Language: | English |
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Wiley
2013-01-01
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| Series: | Case Reports in Cardiology |
| Online Access: | http://dx.doi.org/10.1155/2013/842606 |
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| author | T. El Houari I. Haddiya N. El Ouafi Z. Bazid |
| author_facet | T. El Houari I. Haddiya N. El Ouafi Z. Bazid |
| author_sort | T. El Houari |
| collection | DOAJ |
| description | Calcium channel blockers (CCBs) are prescribed in a wide variety of cardiovascular conditions. Nevertheless, they remain a major cause of cardiovascular drug overdose that often leads to a lethal outcome. We report the case of an intoxication with amlodipine, which caused severe hypotension, in a young woman. The patient was initially treated with fluids, calcium gluconate, and Dobutamine without effect. She then received hyperinsulinemia euglycemia therapy. A rise in blood pressure (BP) was observed two hours after insulin was started. The next day, the insulin infusion was stopped and seven days later the patient was discharged from the hospital after psychiatric consultation. The positive inotropic effect of insulin therapy in our patient supports previous findings that suggest its use as a first-line therapy in the management of CCBs overdose. |
| format | Article |
| id | doaj-art-c331a2a2b03d4f73bfb8ce2dc1aad4ff |
| institution | DOAJ |
| issn | 2090-6404 2090-6412 |
| language | English |
| publishDate | 2013-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Cardiology |
| spelling | doaj-art-c331a2a2b03d4f73bfb8ce2dc1aad4ff2025-08-20T03:23:15ZengWileyCase Reports in Cardiology2090-64042090-64122013-01-01201310.1155/2013/842606842606A Survival Case in a Severe Amlodipine IntoxicationT. El Houari0I. Haddiya1N. El Ouafi2Z. Bazid3Department of Cardiology, Faculty of Medicine, University Mohamed First, Oujda, MoroccoDepartment of Nephrology, Faculty of Medicine, University Mohamed First, Oujda, MoroccoDepartment of Cardiology, Faculty of Medicine, University Mohamed First, Oujda, MoroccoDepartment of Cardiology, Faculty of Medicine, University Mohamed First, Oujda, MoroccoCalcium channel blockers (CCBs) are prescribed in a wide variety of cardiovascular conditions. Nevertheless, they remain a major cause of cardiovascular drug overdose that often leads to a lethal outcome. We report the case of an intoxication with amlodipine, which caused severe hypotension, in a young woman. The patient was initially treated with fluids, calcium gluconate, and Dobutamine without effect. She then received hyperinsulinemia euglycemia therapy. A rise in blood pressure (BP) was observed two hours after insulin was started. The next day, the insulin infusion was stopped and seven days later the patient was discharged from the hospital after psychiatric consultation. The positive inotropic effect of insulin therapy in our patient supports previous findings that suggest its use as a first-line therapy in the management of CCBs overdose.http://dx.doi.org/10.1155/2013/842606 |
| spellingShingle | T. El Houari I. Haddiya N. El Ouafi Z. Bazid A Survival Case in a Severe Amlodipine Intoxication Case Reports in Cardiology |
| title | A Survival Case in a Severe Amlodipine Intoxication |
| title_full | A Survival Case in a Severe Amlodipine Intoxication |
| title_fullStr | A Survival Case in a Severe Amlodipine Intoxication |
| title_full_unstemmed | A Survival Case in a Severe Amlodipine Intoxication |
| title_short | A Survival Case in a Severe Amlodipine Intoxication |
| title_sort | survival case in a severe amlodipine intoxication |
| url | http://dx.doi.org/10.1155/2013/842606 |
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