Integrated transcriptomic and metabolomic analysis reveals the effects of EMMPRIN on nucleotide metabolism and 1C metabolism in AS mouse BMDMs

Integrated transcriptomic and metabolomic analysis reveals the effects of EMMPRIN on nucleotide metabolism and 1C metabolism in AS mouse BMDMs

BackgroundExtracellular matrix metalloproteinase inducer (EMMPRIN) has been considered as a key promoting factor in atherosclerosis (AS). Some studies have shown that regulating EMMPRIN expression in bone marrow-derived macrophages (BMDMs) of ApoE−/− mice can affect plaque stability, but the mechani...

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Bibliographic Details
Main Authors: Yun Zhang, Diyuan Zhang, Zulong Xie, Tianli Xia, Lili Zou, Tao Wang, Li Zhong, Zhuo Zeng, Lingying Wang, Guozhu Chen, Xing Liang
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-03-01
Series:Frontiers in Molecular Biosciences
Subjects:
EMMPRIN
atherosclerosis
metabolomic
transcriptomic
BMDMs
nucleotide metabolism
Online Access:https://www.frontiersin.org/articles/10.3389/fmolb.2024.1460186/full
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https://www.frontiersin.org/articles/10.3389/fmolb.2024.1460186/full

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