α-Glucosidase isoform G contributes to heme detoxification in Rhodnius prolixus and its knockdown affects Trypanosoma cruzi metacyclogenesis

α-Glucosidase isoform G contributes to heme detoxification in Rhodnius prolixus and its knockdown affects Trypanosoma cruzi metacyclogenesis

The triatomine bug Rhodnius prolixus is a hematophagous hemipteran and a primary vector of Trypanosoma cruzi, the causative agent of Chagas' disease (CD), in Central America and Northern South America. Blood-feeding poses significant challenges for hematophagous organisms, particularly due to t...

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Bibliographic Details
Main Authors: Fernanda Ferreira Maissner, Carina Azevedo Oliveira Silva, André Borges Farias, Evenilton Pessoa Costa, José Luciano Nepomuceno-Silva, José Roberto da Silva, Flávia Borges Mury
Format: Article
Language:English
Published: Elsevier 2024-01-01
Series:Current Research in Insect Science
Subjects:
American trypanosomiasis
Digestion
Heme
Perimicrovillar membranes
Vector-pathogen interaction
Online Access:http://www.sciencedirect.com/science/article/pii/S2666515824000301
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