Small extracellular vesicles enhance the survival of Sca-1+ cardiac stem cells against ROS-induced ischemic-reoxygenation injury in vitro
Abstract Background Ischemic reperfusion (IR) generates reactive oxygen species (ROS) that inevitably result in myocardial cell death and heart failure. The regenerative power of cardiac progenitor/stem pools (CSCs), especially the Sca1+ population, in response to IR injury remains unclear. Methods...
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| Main Authors: | Radwa A. Mehanna, Hagar Elkafrawy, Marwa M. Essawy, Samar S. Ibrahim, Ashraf K. Awaad, Nehal A. Khalil, Marwa A. Kholief, Abeer Sallam, Heba A. Hamed, Mona A. Barkat, Mohamed F. ElKady, Eman H. Thabet |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMC
2025-03-01
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| Series: | Biological Research |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s40659-025-00593-7 |
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