Case Report: Two cases of chemotherapy refractory aggressive variant prostate cancer with extreme durable response to PARP inhibitor

Case Report: Two cases of chemotherapy refractory aggressive variant prostate cancer with extreme durable response to PARP inhibitor

BackgroundAggressive variant prostate cancer (AVPC) represents a distinct clinical subset characterized by resistance to novel hormone therapies and an unfavorable prognosis, frequently associated with the concurrent loss of tumor suppressor genes (TSG) such as PTEN, RB1, and TP53. While the progres...

Full description

Saved in:
Bibliographic Details
Main Authors: Bohao Jiang, Yifan Bi, Yiming Chen, Jianbin Bi, Jian Deng, Gejun Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-04-01
Series:Frontiers in Oncology
Subjects:
prostate cancer
aggressive variant prostate cancer
treatment
PARP inhibitor
chemotherapy
radiotherapy
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2025.1533627/full
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://www.frontiersin.org/articles/10.3389/fonc.2025.1533627/full

Similar Items