Targeting conformational changes in C‐reactive protein to inhibit pro‐inflammatory actions
Abstract C‐reactive protein (CRP) is a marker of acute inflammation and modulator of host defense against infections. CRP exists in conformationally distinct forms that exhibit opposing biological functions and could amplify tissue damage. Therefore, therapies that efficiently target the deleterious...
Saved in:
| Main Author: | János G Filep |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Springer Nature
2022-12-01
|
| Series: | EMBO Molecular Medicine |
| Online Access: | https://doi.org/10.15252/emmm.202217003 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
A novel phosphocholine‐mimetic inhibits a pro‐inflammatory conformational change in C‐reactive protein
by: Johannes Zeller, et al.
Published: (2022-12-01) -
C-reactive protein modulates lipid mediators in a pro-inflammatory direction
by: Makoto Kurano, et al.
Published: (2025-08-01) -
Editorial: Targeting the interleukin-1β/interleukin-6/C-reactive protein pathway in clinical medicine - a road map to clinical trial design
by: Jan Torzewski, et al.
Published: (2025-06-01) -
C-reactive protein conformations and their association with the IL-1β/IL-6 pathway in ocular inflammatory conditions
by: Mercedes S. Nabaes Jodar, et al.
Published: (2025-05-01) -
Study on the correlation between c-reactive protein, albumin and c-reactive pro-tein/albumin ratio with disease activity of ulcerative colitis
by: Gulibusidan·Wushoer, et al.
Published: (2021-10-01)