Targeting conformational changes in C‐reactive protein to inhibit pro‐inflammatory actions

Abstract C‐reactive protein (CRP) is a marker of acute inflammation and modulator of host defense against infections. CRP exists in conformationally distinct forms that exhibit opposing biological functions and could amplify tissue damage. Therefore, therapies that efficiently target the deleterious...

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Bibliographic Details
Main Author: János G Filep
Format: Article
Language:English
Published: Springer Nature 2022-12-01
Series:EMBO Molecular Medicine
Online Access:https://doi.org/10.15252/emmm.202217003
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