Development and validation of a nomogram for predicting immune-related thyroid dysfunction during immunotherapy in non-small cell lung cancer: a prospective cohort study in China

Development and validation of a nomogram for predicting immune-related thyroid dysfunction during immunotherapy in non-small cell lung cancer: a prospective cohort study in China

BackgroundImmune checkpoint inhibitors (ICIs) have improved survival for non-small cell lung cancer (NSCLC) patients, but immune-related adverse events (irAEs), like immune-mediated thyroid dysfunction (IMTD), have been reported. IMTD causes irreversible thyroid damage, affecting NSCLC patients’ qua...

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Bibliographic Details
Main Authors: Qianjie Xu, Yuliang Yuan, Xiaosheng Li, Lulu Wang, Wei Zhou, Zuhai Hu, Haike Lei, Yongzhong Wu
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-07-01
Series:Frontiers in Immunology
Subjects:
ICIS
immune-mediated thyroid dysfunction
nomogram
risk model
NSCLC
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1611956/full
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https://www.frontiersin.org/articles/10.3389/fimmu.2025.1611956/full

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