Cholesterol: The driving force behind the remodeling of tumor microenvironment in colorectal cancer

Cholesterol: The driving force behind the remodeling of tumor microenvironment in colorectal cancer

Essential membrane components and metabolites with a wide range of biological roles are both produced by cholesterol metabolism. Cell-intrinsic and cell-extrinsic stimuli alter cholesterol metabolism in the tumor microenvironment (TME), which in turn encourages colorectal carcinogenesis. Metabolites...

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Bibliographic Details
Main Authors: Ke Wang, Yuanyuan Zhang, Chengshuai Si, Yuepeng Cao, Peng Shao, Pei Zhang, Nannan Wang, Guoqing Su, Jinghang Qian, Liu Yang
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:Heliyon
Subjects:
CRC
Cholesterol
Biomarkers
Targeted therapy
Tumor microenvironment remodeling
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844024154564
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