Lactobacillus lysates protect oral epithelial cells from pathogen-associated damage, increase secretion of pro-inflammatory cytokines and enhance barrier integrity

Abstract Periodontitis is a chronic gum disease characterised by inflammation and the loss of bone. We have explored the potential prophylactic effects of lysates from four Lactobacillus strains against the toxic effects of three periodontal pathogens (Porphyromonas gingivalis, Fusobacterium nucleat...

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Bibliographic Details
Main Authors: Steven D. Mercer, Christopher Doherty, Gurdeep Singh, Thomas Willmott, Tanaporn Cheesapcharoen, Rawee Teanpaisan, Catherine O’Neill, Ruth G. Ledder, Andrew J. McBain
Format: Article
Language:English
Published: Nature Portfolio 2025-02-01
Series:Scientific Reports
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Online Access:https://doi.org/10.1038/s41598-025-86914-y
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