Lysosome–Iron–Mitochondria Axis in Osteoclasts: Iron as a Central Player

Osteoporosis, a widespread skeletal disorder, arises from excessive bone loss, heightening fragility and fracture risk. Osteoclasts, the major type of bone-resorbing cells, are believed to contribute to this loss. Osteoclast bone resorption relies on 2 important organelles: lysosomes for matrix degr...

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Bibliographic Details
Main Authors: Shengnan Qin, Kathleen Davern, Scott G. Wilson, Kai Chen, Aiguo Li, Jiake Xu
Format: Article
Language:English
Published: American Association for the Advancement of Science (AAAS) 2025-01-01
Series:Research
Online Access:https://spj.science.org/doi/10.34133/research.0840
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