Lactucin ameliorates FFA-induced steatosis in HepG2 cells by modulating mitochondrial homeostasis through the SIRT1/PGC-1α signaling axis

Lactucin ameliorates FFA-induced steatosis in HepG2 cells by modulating mitochondrial homeostasis through the SIRT1/PGC-1α signaling axis

Nonalcoholic fatty liver disease is a complex disease involving abnormal liver metabolism. Its strong association with metabolic dysfunction has led to a change in nomenclature to metabolism dysfunction-associated fatty liver disease (MAFLD). MAFLD pathogenesis involves abnormal accumulation of hepa...

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Bibliographic Details
Main Authors: Yi Lei, Xiao-li Ma, Tong Liu, Meng-jiao Wang, Jin-sen Kang, Jian Yang, Na Mi
Format: Article
Language:English
Published: Elsevier 2024-11-01
Series:Heliyon
Subjects:
Lactucin
Mitochondrial biosynthesis
Mitochondrial dynamics
HepG2 cells
Online Access:http://www.sciencedirect.com/science/article/pii/S240584402415921X
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