Computational design and evaluation of a polyvalent vaccine for viral nervous necrosis (VNN) in fish to combat Betanodavirus infection

Computational design and evaluation of a polyvalent vaccine for viral nervous necrosis (VNN) in fish to combat Betanodavirus infection

Abstract Viral nervous necrosis (VNN) poses a significant threat to the aquaculture industry, causing substantial losses and economic burdens. The disease, attributed to nervous necrosis viruses within the Betanodavirus genus, is particularly pervasive in the Mediterranean region, affecting various...

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Main Authors: Abu Tayab Moin, Nurul Amin Rani, Yasin Arafath Sharker, Tanbir Ahammed, Umme Sadea Rahman, Sadia Yasmin, Irfan Haque Ratul, Shanjida Akter Joyoti, Muhammad Sakib Musa, Mizan Ur Rahaman, Dipta Biswas, Md Hazrat Ali, S. M. Murshid Ul Alam, Rajesh B. Patil, Rashed Un Nabi, Mohammad Helal Uddin
Format: Article
Language:English
Published: Nature Portfolio 2024-11-01
Series:Scientific Reports
Subjects:
Viral nervous necrosis (VNN)
Fish vaccine
Betanodavirus
Multi-epitope vaccine
Immunoinformatics
Molecular dynamics simulation
Online Access:https://doi.org/10.1038/s41598-024-72116-5
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https://doi.org/10.1038/s41598-024-72116-5

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