GSDMD is a novel predictive biomarker for immunotherapy response: in the pan-cancer and single cell landscapes

BackgroundGasdermin D (GSDMD), a key executor of pyroptosis, has been implicated in modulating the tumor immune microenvironment. However, its role as a predictive biomarker for immunotherapy response remains unclear.MethodsWe conducted a pan-cancer analysis of GSDMD expression across TCGA datasets...

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Bibliographic Details
Main Authors: Li Juan Huang, Feng Chen, Lin Chen, Shi Tong Zhan, Ming Min Liu, Jiang Dong Xiang, Qin Yi Zhang, Ye Yang
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-05-01
Series:Frontiers in Immunology
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Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1570901/full
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