Elabela alleviates cuproptosis and vascular calcification in vitaminD3- overloaded mice via regulation of the PPAR-γ /FDX1 signaling

Elabela alleviates cuproptosis and vascular calcification in vitaminD3- overloaded mice via regulation of the PPAR-γ /FDX1 signaling

Abstract Background Vascular calcification is a crucial pathophysiological process associated with age-related cardiovascular diseases. Elabela, a recently identified peptide, has emerged as a significant player in the regulation of cardiovascular function and homeostasis. However, the effects and u...

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Main Authors: Rui-Qiang Qi, Yu-Fei Chen, Jing Cheng, Jia-Wei Song, Yi-Hang Chen, Si-Yuan Wang, Ying Liu, Kai-Xin Yan, Xiao-Yan Liu, Jing Li, Jiu-Chang Zhong
Format: Article
Language:English
Published: BMC 2024-11-01
Series:Molecular Medicine
Subjects:
Elabela
Cuproptosis
Peroxisome proliferators-activated receptor-γ
Vascular calcification
Vascular smooth muscle cells
Online Access:https://doi.org/10.1186/s10020-024-00997-3
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https://doi.org/10.1186/s10020-024-00997-3

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