Picolinate-mediated immunomodulation: insights from Mendelian randomization on the role of NK cell percentage in the pathogenesis of lichen planus

Picolinate-mediated immunomodulation: insights from Mendelian randomization on the role of NK cell percentage in the pathogenesis of lichen planus

BackgroundLichen planus (LP), an autoimmune disorder, remains incompletely understood in terms of its etiological mechanisms. This study aims to elucidate causal relationships among immune cell populations, plasma metabolites, and lichen planus using Mendelian randomization (MR) techniques.MethodsEm...

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Bibliographic Details
Main Authors: Jianye Cao, Tiantao Du, Jian Li, Baiyu Chen, Xianting Xie, Guoshu Zhang, Jia Feng, Tao Xu
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-12-01
Series:Frontiers in Immunology
Subjects:
immune cells
Lichen Planus
mediation analysis
Mendelian randomization
plasma metabolites
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1464479/full
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https://www.frontiersin.org/articles/10.3389/fimmu.2024.1464479/full

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