Clinical and cost-effectiveness of detailed anomaly ultrasound screening in the first trimester: a mixed-methods study

Clinical and cost-effectiveness of detailed anomaly ultrasound screening in the first trimester: a mixed-methods study

Background In the United Kingdom, pregnant women are offered two scans: at 11–14 and 18–20 weeks’ gestation. Current guidance supports fetal anatomical screening at the second scan, but evidence suggests earlier detection is possible. Objectives To determine clinical and cost-effectiveness of a deta...

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Main Authors: Jehan N Karim, Helen Campbell, Pranav Pandya, Edward C F Wilson, Zarko Alfirevic, Trish Chudleigh, Elizabeth Duff, Jane Fisher, Hilary Goodman, Lisa Hinton, Christos Ioannou, Edmund Juszczak, Louise Linsell, Heather L Longworth, Kypros H Nicolaides, Anne Rhodes, Gordon Smith, Basky Thilaganathan, Jim Thornton, Gillian Yaz, Oliver Rivero-Arias, Aris T Papageorghiou
Format: Article
Language:English
Published: NIHR Journals Library 2025-05-01
Series:Health Technology Assessment
Subjects:
population screening
sensitivity
specificity
fetal abnormalities
first trimester
ultrasound
pregnancy
health economics
value of information
systematic review
Online Access:https://doi.org/10.3310/NLTP7102
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https://doi.org/10.3310/NLTP7102

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