Accumulation of Bile in the Gallbladder: Evaluation by means of Serial Dynamic Contrast-Enhanced Magnetic Resonance Cholangiography with Gadolinium Ethoxybenzyl Diethylenetriaminepentaacetic Acid
The aim of this study was to evaluate the process of biliary excretion of gadolinium ethoxybenzyl diethylenetriaminepentaacetic acid (Gd-EOB-DTPA) into the biliary tract and to assess the accumulation patterns in the gallbladder using MR cholangiography obtained with Gd-EOB-DTPA which is a liver-spe...
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| Format: | Article |
| Language: | English |
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Wiley
2014-01-01
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| Series: | Gastroenterology Research and Practice |
| Online Access: | http://dx.doi.org/10.1155/2014/479067 |
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| author | Tsutomu Tamada Katsuyoshi Ito Kazuya Yasokawa Atsushi Higaki Akihiko Kanki Yasufumi Noda Akira Yamamoto |
| author_facet | Tsutomu Tamada Katsuyoshi Ito Kazuya Yasokawa Atsushi Higaki Akihiko Kanki Yasufumi Noda Akira Yamamoto |
| author_sort | Tsutomu Tamada |
| collection | DOAJ |
| description | The aim of this study was to evaluate the process of biliary excretion of gadolinium ethoxybenzyl diethylenetriaminepentaacetic acid (Gd-EOB-DTPA) into the biliary tract and to assess the accumulation patterns in the gallbladder using MR cholangiography obtained with Gd-EOB-DTPA which is a liver-specific hepatobiliary contrast agent. Seventy-five patients underwent Gd-EOB-DTPA enhanced MR imaging. Serial multiphasic hepatobiliary phase imaging was qualitatively reviewed to evaluate the process of the biliary excretion of contrast agent into the bile duct and the gallbladder. The accumulation pattern of contrast agent into gallbladder was classified into two groups (group 1 = orthodromic type and group 2 = delayed type). Furthermore, the results in differences of the presence of T1 hyperintense bile or sludge of gallbladder, gall stones, wall thickening of gallbladder, chronic liver disease, and liver cirrhosis between two groups were compared. Forty-eight of 75 patients (64%) were included in group 1, and remaining 27 (36%) were in group 2. The frequency of the presence of T1 hyperintense bile or sludge of gallbladder was significantly higher in patients with group 2 than that in patients with group 1 (P=0.041). MR cholangiography obtained with Gd-EOB-DTPA showed that there may be an association between the biliary accumulation pattern in the gallbladder and the pathological condition. |
| format | Article |
| id | doaj-art-c1ea1799a33a4fa5a20159e3dad74741 |
| institution | Kabale University |
| issn | 1687-6121 1687-630X |
| language | English |
| publishDate | 2014-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Gastroenterology Research and Practice |
| spelling | doaj-art-c1ea1799a33a4fa5a20159e3dad747412025-02-03T01:31:24ZengWileyGastroenterology Research and Practice1687-61211687-630X2014-01-01201410.1155/2014/479067479067Accumulation of Bile in the Gallbladder: Evaluation by means of Serial Dynamic Contrast-Enhanced Magnetic Resonance Cholangiography with Gadolinium Ethoxybenzyl Diethylenetriaminepentaacetic AcidTsutomu Tamada0Katsuyoshi Ito1Kazuya Yasokawa2Atsushi Higaki3Akihiko Kanki4Yasufumi Noda5Akira Yamamoto6Department of Radiology, Kawasaki Medical School, 577 Matsushima, Kurashiki City, Okayama 701-0192, JapanDepartment of Radiology, Kawasaki Medical School, 577 Matsushima, Kurashiki City, Okayama 701-0192, JapanDepartment of Radiology, Kawasaki Medical School, 577 Matsushima, Kurashiki City, Okayama 701-0192, JapanDepartment of Radiology, Kawasaki Medical School, 577 Matsushima, Kurashiki City, Okayama 701-0192, JapanDepartment of Radiology, Kawasaki Medical School, 577 Matsushima, Kurashiki City, Okayama 701-0192, JapanDepartment of Radiology, Kawasaki Medical School, 577 Matsushima, Kurashiki City, Okayama 701-0192, JapanDepartment of Radiology, Kawasaki Medical School, 577 Matsushima, Kurashiki City, Okayama 701-0192, JapanThe aim of this study was to evaluate the process of biliary excretion of gadolinium ethoxybenzyl diethylenetriaminepentaacetic acid (Gd-EOB-DTPA) into the biliary tract and to assess the accumulation patterns in the gallbladder using MR cholangiography obtained with Gd-EOB-DTPA which is a liver-specific hepatobiliary contrast agent. Seventy-five patients underwent Gd-EOB-DTPA enhanced MR imaging. Serial multiphasic hepatobiliary phase imaging was qualitatively reviewed to evaluate the process of the biliary excretion of contrast agent into the bile duct and the gallbladder. The accumulation pattern of contrast agent into gallbladder was classified into two groups (group 1 = orthodromic type and group 2 = delayed type). Furthermore, the results in differences of the presence of T1 hyperintense bile or sludge of gallbladder, gall stones, wall thickening of gallbladder, chronic liver disease, and liver cirrhosis between two groups were compared. Forty-eight of 75 patients (64%) were included in group 1, and remaining 27 (36%) were in group 2. The frequency of the presence of T1 hyperintense bile or sludge of gallbladder was significantly higher in patients with group 2 than that in patients with group 1 (P=0.041). MR cholangiography obtained with Gd-EOB-DTPA showed that there may be an association between the biliary accumulation pattern in the gallbladder and the pathological condition.http://dx.doi.org/10.1155/2014/479067 |
| spellingShingle | Tsutomu Tamada Katsuyoshi Ito Kazuya Yasokawa Atsushi Higaki Akihiko Kanki Yasufumi Noda Akira Yamamoto Accumulation of Bile in the Gallbladder: Evaluation by means of Serial Dynamic Contrast-Enhanced Magnetic Resonance Cholangiography with Gadolinium Ethoxybenzyl Diethylenetriaminepentaacetic Acid Gastroenterology Research and Practice |
| title | Accumulation of Bile in the Gallbladder: Evaluation by means of Serial Dynamic Contrast-Enhanced Magnetic Resonance Cholangiography with Gadolinium Ethoxybenzyl Diethylenetriaminepentaacetic Acid |
| title_full | Accumulation of Bile in the Gallbladder: Evaluation by means of Serial Dynamic Contrast-Enhanced Magnetic Resonance Cholangiography with Gadolinium Ethoxybenzyl Diethylenetriaminepentaacetic Acid |
| title_fullStr | Accumulation of Bile in the Gallbladder: Evaluation by means of Serial Dynamic Contrast-Enhanced Magnetic Resonance Cholangiography with Gadolinium Ethoxybenzyl Diethylenetriaminepentaacetic Acid |
| title_full_unstemmed | Accumulation of Bile in the Gallbladder: Evaluation by means of Serial Dynamic Contrast-Enhanced Magnetic Resonance Cholangiography with Gadolinium Ethoxybenzyl Diethylenetriaminepentaacetic Acid |
| title_short | Accumulation of Bile in the Gallbladder: Evaluation by means of Serial Dynamic Contrast-Enhanced Magnetic Resonance Cholangiography with Gadolinium Ethoxybenzyl Diethylenetriaminepentaacetic Acid |
| title_sort | accumulation of bile in the gallbladder evaluation by means of serial dynamic contrast enhanced magnetic resonance cholangiography with gadolinium ethoxybenzyl diethylenetriaminepentaacetic acid |
| url | http://dx.doi.org/10.1155/2014/479067 |
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