Immunohistochemical and molecular evolutionary features of jejunoileal adenocarcinoma unveiled through comparative analysis with colorectal adenocarcinoma

Immunohistochemical and molecular evolutionary features of jejunoileal adenocarcinoma unveiled through comparative analysis with colorectal adenocarcinoma

Jejunoileal adenocarcinoma (JIAC) is a rare type of malignancy, the clinicopathological, genetic, and evolutionary characteristics of which have rarely been reported. In this study, 52 patients with JIAC and 182 patients with colorectal adenocarcinoma (CRAC) were recruited. Immunohistochemical analy...

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Main Authors: Rei Ishikawa, Hidetaka Yamada, Hirotomo Saitsu, Ryosuke Miyazaki, Juri Takahashi, Rino Takinami, Satoshi Baba, Mitsuko Nakashima, Moriya Iwaizumi, Satoshi Osawa, Hideya Kawasaki, Yoshifumi Arai, Yoshiro Otsuki, Hiroshi Ogawa, Hiroki Mori, Fumihiko Tanioka, Shioto Suzuki, Kazuyo Yasuda, Makoto Suzuki, Haruhiko Sugimura, Kazuya Shinmura
Format: Article
Language:English
Published: Elsevier 2025-08-01
Series:Neoplasia: An International Journal for Oncology Research
Subjects:
Small bowel cancer
Immunohistochemical analysis
Whole-exome sequencing
Mismatch repair deficient
Cancer evolutionary history
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558625000594
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