6-Chlorocoumarin Conjugates with Nucleobases and Nucleosides as Potent Anti-Hepatitis C Virus Agents

On the basis of a “chemo-combination strategy”, (6-chloro)coumarin was incorporated to purines and pyrimidines, as well as their corresponding nucleosides, with a –SCH<sub>2</sub>– linker at different positions under alkaline conditions. These conjugates were found to exert an antiviral...

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Bibliographic Details
Main Authors: Shu-Yu Lin, Wen-Chieh Huang, Shwu-Chen Tsay, Johan Neyts, Pieter Leyssen, Chun-Cheng Lin, Kuo Chu Hwang, Jia-Cherng Horng, Jih Ru Hwu
Format: Article
Language:English
Published: MDPI AG 2025-04-01
Series:Molecules
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Online Access:https://www.mdpi.com/1420-3049/30/8/1776
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